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What Is Peyronie’s Disease? Impact on Fertility and Treatment

What Is Peyronie’s Disease? Impact on Fertility and Treatment

Peyronie’s disease is a condition that affects the male reproductive system, causing significant concerns both physically and psychologically. Named after the French surgeon François Gigot de la Peyronie, who first described it in 1743, this condition involves the formation of fibrous scar tissue inside the penis. This scar tissue can cause the penis to bend or curve during erections, leading to pain and potentially affecting sexual function and fertility.

What does Peyronie’s Disease look like?

Visually, Peyronie’s disease can present as a curve, indentation, or even narrowing of the penis. This curvature can be upwards, downwards, or to either side, making erections painful or difficult. The severity of the curvature varies from mild to severe, depending on the individual.

Symptoms of Peyronie’s Disease

Pain: Especially during erections or even without them.

Erectile Dysfunction: Difficulty achieving or maintaining an erection.

Shortening of the Penis: In some cases, due to the scar tissue affecting the length.

Emotional Distress: Anxiety or depression related to changes in sexual function and appearance.

How Common is Peyronie’s Disease?

Peyronie’s disease is more common than often recognized, affecting about 1-3% of adult men. It typically manifests between the ages of 40 and 60, though younger men can also develop it.

Causes of Peyronie’s Disease

The exact cause of Peyronie’s disease isn’t fully understood, but it is believed to involve trauma or injury to the penis, which leads to the formation of scar tissue. Factors such as genetics, autoimmune disorders, and certain connective tissue disorders may also contribute.

Treatments for Peyronie’s Disease

Treatment options for Peyronie’s disease aim to reduce pain, improve penile curvature, and restore sexual function. These may include:

Medications: Oral medications or injections of medications directly into the scar tissue to reduce plaque.

Physical Therapy: Techniques such as penile traction devices or vacuum erection devices may help reduce curvature.

Surgery: In severe cases where other treatments fail, surgical procedures to remove or reposition the scar tissue may be necessary.

Impact on Trying to Conceive

Peyronie’s disease can impact fertility in several ways:

Erectile Dysfunction: Difficulty achieving or maintaining an erection can affect sexual intercourse.

Physical Obstruction: Severe curvature may make intercourse difficult or impossible.

Sperm Quality: Scar tissue and reduced blood flow can impact sperm production and quality.

Importance of Sperm Testing

When trying to conceive with Peyronie’s disease, evaluating sperm quality through testing is crucial. This helps understand if the condition is affecting fertility directly or indirectly. Sperm testing can identify issues such as low sperm count, poor sperm motility, or abnormal sperm morphology, guiding further treatment options.

When to See a Doctor

It’s essential to seek medical advice if you notice any changes in the shape or function of your penis, especially if it’s causing pain or affecting your ability to have sex. Early intervention can help manage symptoms effectively and preserve sexual function and fertility.


Peyronie’s disease is a complex condition that can significantly impact a man’s quality of life, sexual function, and fertility. Understanding its symptoms, causes, and available treatments is crucial for those affected. If you or your partner are struggling with Peyronie’s disease and trying to conceive, consulting with healthcare professionals specializing in sexual health and fertility can provide guidance on the best course of action. Advances in medical treatment and technology offer hope for managing the condition effectively and improving outcomes for couples hoping to start a family.

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